乳房醫學中心
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現職
生醫發展中心主任
教育部部定副教授
一般外科資深主治醫師主要學歷
陽明大學藥理學研究所博士
中山醫學大學醫學系主要經歷
教育部部定副教授
馬偕紀念醫院一般外科主任
馬偕紀念醫院一般外科資深主治醫師其他相關
外科專科醫師
乳房專科醫師
消化系外科專科醫師
肝移植外科醫師
內視鏡外科專科醫師
主治項目或專長
乳癌及乳房腫瘤手術、肝膽腫瘤手術、腹部急症
論文研究
1. Yang PS, Wang JJ, Tsai TH, Wang YH, Jan WC, Cheng SP, Chi CW, Hsu YC. Anticolorectal cancer effects and pharmacokinetic application of 2, 2-Bis [4-(4-amino-3-hydroxyphenoxy) phenyl] adamantine. Int J Clin Exp Med. 2015 Sep 15;8(9):14805-15. eCollection 2015. 2. Yang PS, Wang JJ, Wang YH, Jan WC, Cheng SP, Hsu YC. 1,6-Bis[4-(4-amino-3-hydroxyphenoxy)phenyl] diamantane potentiates in vitro and in vivo antitumor effects of irinotecan on human colorectal cancer cells. Oncol Lett. 2016 May;11(5):3551-3557 3. Tu SH, Lin YC, Huang CC, Yang PS, Chang HW, Chang CH, Wu CH, Chen LC, Ho YS. Protein phosphatase Mg2+/Mn2+ dependent 1F promotes smoking-induced breast cancer by inactivating phosphorylated-p53-induced signals. Oncotarget. 2016 Nov 22;7(47):77516-77531. doi: 10.18632/oncotarget.12717. 4. Cheng SP, Yang PS, Chien MN, Chen MJ, Lee JJ, Liu CL. Aberrant expression of tumor-associated carbohydrate antigen Globo H in thyroid carcinoma. J Surg Oncol. 2016 Dec;114(7):853-858. doi: 10.1002/jso.24479. 5. Chien MN, Yang PS, Lee JJ, Wang TY, Hsu YC, Cheng SP. Recurrence-associated genes in papillary thyroid cancer: An analysis of data from The Cancer Genome Atlas. Surgery. 2017 Jun;161(6):1642-1650. doi: 10.1016/j.surg.2016.12.039. 6. Tsai CC, Yang PS, Liu CL, Wu CJ, Hsu YC, Cheng SP. Comparison of topical mupirocin and gentamicin in the prevention of peritoneal dialysis-related infections: A systematic review and meta-analysis. Am J Surg. 2017 Mar 15. pii: S0002-9610(16)30710-3. doi: 10.1016/j.amjsurg.2017.03.005. 7. Tsai CL, Liu WL, Hsu FM, Yang PS, Yen RF, Tzen KY, Cheng AL, Chen PJ, Cheng JC. Targeting Histone deacetylase 4/Ubc9 impairs DNA repair for radiosensitization of hepatocellular carcinoma cells. Hepatology. 2017 Jun 23. doi: 10.1002/hep.29328. 8. Wang CL, Yang PS, Tsao JT, Jayakumar T, Wang MJ, Sheu JR, Chou DS. Mechanism of free radical generation in platelets and primary hepatocytes: A novel electron spin resonance study. Mol Med Rep. 2018 Jan;17(1):2061-2069. doi: 10.3892/mmr.2017.8058. 9. Yang PS, Liu CL, Liu TP, Chen HH, Wu CJ, Cheng SP. Parathyroidectomy decreases neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios. J Surg Res. 2018 Apr;224:169-175. doi: 10.1016/j.jss.2017.12.016. 10. Liu CL, Yang PS, Chien MN, Chang YC, Lin CH, Cheng SP. Expression of serine peptidase inhibitor Kunitz type 1 in differentiated thyroid cancer. Histochem Cell Biol. 2018 Jun;149(6):635-644. doi: 10.1007/s00418-018-1660-2. 11. Chou D, Peng HY, Lin TB, Lai CY, Hsieh MC, Wen YC, Lee AS, Wang HH, Yang PS, Chen GD, Ho YC. (2R,6R)-hydroxynorketamine rescues chronic stress-induced depression-like behavior through its actions in the midbrain periaqueductal gray. Neuropharmacology. 2018 Sep 1;139:1-12. doi: 10.1016/j.neuropharm.2018.06.033. 12. Lee WH, Chen LC, Lee CJ, Huang CC, Ho YS, Yang PS, Ho CT, Chang HL, Lin IH, Chang HW, Liu YR, Wu CH, Tu SH. DNA primase polypeptide 1 (PRIM1) involves in estrogen-induced breast cancer formation through activation of the G2/M cell cycle checkpoint. Int J Cancer. 2018 Aug 11. doi: 10.1002/ijc.31788. 13. Chien MN, Yang PS, Hsu YC, Liu TP, Lee JJ, Cheng SP. Transcriptome analysis of papillary thyroid cancer harboring telomerase reverse transcriptase promoter mutation. Head Neck. 2018 Aug 13. doi: 10.1002/hed.25385. 14. Yang PS, Hsu YC, Lee JJ, Chen MJ, Huang SY, Cheng SP. Heme Oxygenase-1 Inhibitors Induce Cell Cycle Arrest and Suppress Tumor Growth in Thyroid Cancer Cells. Int J Mol Sci. 2018 Aug 24;19(9). pii: E2502. doi: 10.3390/ijms19092502. 15. Su YW, Hung CY, Lam HB, Chang YC, Yang PS*. A Single Institution Experience of Incorporation of Cisplatin into Adjuvant Chemotherapy for Patients With Triple-Negative Breast Cancer of Unknown BRCA Mutation Status. Clin Med Insights Oncol. 2018 Aug 21;12:1179554918794672. doi: 10.1177/1179554918794672. 16. Lai CY, Hsieh MC, Ho YC, Wang HH, Chou D, Wen YC, Yang PS, Cheng JK, Peng HY. Spinal RNF20-Mediated Histone H2B Monoubiquitylation Regulates mGluR5 Transcription for Neuropathic Allodynia. J Neurosci. 2018 Oct 24;38(43):9160-9174. doi: 10.1523/JNEUROSCI.1069-18.2018. Epub 2018 Sep 10. 17. Yang PS, Hsu HH, Hsu TC, Chen MJ, Wang CD, Yu SL, Hsu YC, Li KC. Genome-Wide Scan for Copy Number Alteration Association with Relapse-Free Survival in Colorectal Cancer with Liver Metastasis Patients. J Clin Med. 2018 Nov 18;7(11). pii: E446. doi: 10.3390/jcm7110446. 18. Lee F, Yang PS, Chien MN, Lee JJ, Leung CH, Cheng SP. An Increased Neutrophil-to-Lymphocyte Ratio Predicts Incomplete Response to Therapy in Differentiated Thyroid Cancer. Int J Med Sci. 2018 Nov 23;15(14):1757-1763. doi: 10.7150/ijms.28498. eCollection 2018. 19. Yang PS*, Liu CP, Hsu YC, Chen CF, Lee CC, Cheng SP. A Novel Prediction Model for Bloodstream Infections in Hepatobiliary-Pancreatic Surgery Patients. World J Surg. 2019 May;43(5):1294-1302. doi: 10.1007/s00268-018-04903-x.PMID: 30603763 20. Tsai CH, Yang PS, Lee JJ, Liu TP, Kuo CY, Cheng SP. Effects of Preoperative Iodine Administration on Thyroidectomy for Hyperthyroidism: A Systematic Review and Meta-analysis. Otolaryngol Head Neck Surg. 2019 Jun;160(6):993-1002. doi: 10.1177/0194599819829052. 21. Yang PS, Lee YH, Chung CF, Chang YC, Wang MY, Lo C, Tsai LW, Shih KH, Lei J, Yu BL, Cheng SH, Huang CS. A preliminary report of head-to-head comparison of 18-gene-based clinical-genomic model and oncotype DX 21-gene assay for predicting recurrence of early-stage breast cancer. Jpn J Clin Oncol. 2019 Dec 18;49(11):1029-1036. 22. Liu CL, Yang PS, Wang TY, Huang SY, Kuo YH, Cheng SP. PGC1α downregulation and glycolytic phenotype in thyroid cancer. J Cancer. 2019 Jun 9;10(16):3819-3829. doi: 10.7150/jca.30018. eCollection 2019. 23. Lam HB, Yang PS, Chien MN, Lee JJ, Chao LF, Cheng SP. Association between neutrophil-to-lymphocyte ratio and parathyroid hormone in patients with primary hyperparathyroidism. Arch Med Sci. 2019 Jul;15(4):880-886. doi: 10.5114/aoms.2018.74758. Epub 2018 Mar 28. 24. Chu TP, Yang PS, Lee JJ, Wu CJ, Cheng SP. Increasing Age Hinders the Decline in B-Type Natriuretic Peptide Following Parathyroidectomy in Dialysis Patients. In Vivo. 2019 Sep-Oct;33(5):1691-1696. doi: 10.21873/invivo.11657. 25. Lin TB, Lai CY, Hsieh MC, Ho YC, Wang HH, Yang PS, Cheng JK, Chen GD, Ng SC, Peng HY. Inhibiting MLL1-WDR5 interaction ameliorates neuropathic allodynia by attenuating histone H3 lysine 4 trimethylation-dependent spinal mGluR5 transcription. Pain . 2020 Apr 23. doi: 10.1097/j.pain.0000000000001898. 26. Yang PS, Peng HY, Lin TB, Hsieh MC, Lai CY, Lee AS, Wang HH, Ho YC. NMDA receptor partial agonist GLYX-13 alleviates chronic stress-induced depression-like behavior through enhancement of AMPA receptor function in the periaqueductal gray. Neuropharmacology. 2020 Aug 10;178:108269. doi: 10.1016/j.neuropharm.2020.108269.