心臟血管內科系
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現職
- 馬偕醫學院醫學系部定副教授、國防醫學院醫學系臨床教授
- 系/心臟血管中心資深主治醫師
主要學歷
- 英國雪菲爾大學醫學暨生醫科學院臨床科學中心博士 (Ph.D.)
- 中國醫藥大學中國中醫十七屆醫學士 (M.D.)
- 市立高雄中學
主要經歷
- 內科、心臟、重症 (專科醫師、指導醫師)
- 歐洲心臟學會院士 (FESC)
- 馬偕紀念醫院心臟血管中心主任 (2016~2023 July)
- 馬偕紀念醫院心衰竭醫學科主任 (2016~2023 July)
- 中華民國心臟學會理事 (第十七屆, 第十八屆),中華民國超音波學會監事 (第十六屆), 理事 (第十七屆)
- 馬偕紀念醫院心臟內科主任 (2015~2019)
- 行政院科技部生科司心臟血管學門初審委員 (2012~)
- 馬偕紀念醫院內科加護病房主任 (淡水院區2009-2013)
- 台灣醫學教育學會醫學臨床技能測驗考官
- 中華民國心臟學會雜誌執行編輯 (2007-2009)
- 台灣醫院審查醫藥專家 (2008~ ), 國建署戒菸專家 (2020~)
- 「台北國際發明暨技術交易展」- 發明競賽銀牌獎 (2015)
- 馬偕紀念醫院內科部實習醫學生計畫負責人 (2013-2017)
- 教育部部定助理教授
- 馬偕紀念醫院醫教部優良教師 (2013)
- 馬偕紀念醫院優良主治醫師 (2008)
- 中華民國陸軍146師義務役少尉衛生排長兼軍醫官
主治項目或專長
- 心臟衰竭、高血壓、高血脂、代謝症候群、缺氧性心臟病 (心絞痛)、瓣膜性心臟病、週邊血管動脈硬化疾病、心律不整
論文研究
RESEARCH INTERESTS:
1. Ultrasound-based and Non-virus Gene Delivery 2. Impact of aging-related miRNA in the function of human endothelial progenitors
Selected peer-reviewed journal articles:
- Nonviral Gene Therapy Targeting Cardiovascular System. Am J Physiol Heart Circ Physiol. 2012 Sep 15;303(6):H629-38. Invited review. (1st Author)
- The Increase of VEGF Secretion From Endothelial Progenitor Cells Post Ultrasonic VEGF Gene Delivery Enhances The Proliferation and Migration of Endothelial Cells. Ultrasound Med Biol. 2013 Jan;39(1):134-45. (1st A.)
- Enhanced Proliferation of Endothelial Progenitor Cells Post Ultrasonic Microbubble Transfection is pDNA Size-dependent and Contributed by IL-6 Generation. Ultrasound Med Biol. 2019 Jun 24. (Corresponding A.)
- 【馬偕紀念醫院參與冠心病照護品質認證分享】Journal of Healthcare Quality 14(6): 38-40, 2020 November.【醫品雜誌】(1st A.)
- Ultrasonic Microbubble VEGF Gene Delivery Improves Angiogenesis of Senescent Endothelial Progenitor Cells. Scientific Reports. 2021 Jun 29;11(1):13449. (Corresponding A.)
- An Effective Strategy to Activate Physicians to Promote High Cardiovascular Risk Patients to Quit Smoking. Acta Cardiologica Sinica. 2022;38:521_525. (1st A.)
- Hsa-miR-409-3p Regulates Endothelial Progenitor Senescence via PP2A-P38 and Is A Potential Ageing Marker in Humans. Journal of Cellular and Molecular Medicine. 2023 Mar;27(5):687-700. (Corresponding A.)
- Transdermal Nicotine Increases the Number and Function of Endothelial Progenitor Cells in Young Healthy Non-smokers with Safe Hemodynamic Effects. Clinical Pharmacology & Therapeutics. 2024 Jul;116(1):128-135. (Co-corresponding A.)
- Hsa-miR-134-5p predicts cardiovascular risk in circulating mononuclear cells and improves angiogenic action of senescent endothelial progenitor cells. J Cell Mol Med. 2024 Jul;28(13):e18523. doi: 10.1111/jcmm.18523. (Corresponding A.)
*Basic Research Award, Second Prize Winner (Aug 2010) (moderated poster competition)
The Annual Scientific Meeting of Taiwan Society of Lipids and Atherosclerosis
*Basic Research Award, Second Prize Winner (Oct 2011) (Oral presentation competition)
2011 Annual Convention of Taiwan Society of Ultrasound in Medicine
*Basic Research Award, First Prize Winners (Sep 2017, 2018 and 2020) (Moderated poster competition)
The Annual Scientific Meeting of Taiwan Society of Lipids and Atherosclerosis and The Taipei International Vascular Biology Symposium